What is primarily minimized by using ice in a reaction involving NaBH4?

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Using ice in a reaction involving sodium borohydride (NaBH4) is primarily aimed at minimizing the formation of side products. In many reactions, particularly those involving sensitive functional groups or ingredients that may undergo side reactions, controlling the temperature is crucial. Ice (or an ice bath) provides an environment that helps to keep the temperature low, which slows down the reaction rate. This reduction in reaction speed can discourage unwanted side reactions that could produce byproducts and therefore helps in directing the reaction toward the desired product.

Furthermore, lower temperatures can stabilize certain intermediates or reactive species that would otherwise decompose or react in undesired ways at higher temperatures. Consequently, by using ice, chemists can improve the selectivity of the reaction, leading to a more favorable yield of the intended product with minimal byproduct formation. This is particularly important in synthetic chemistry, where the purity of the final compound is a key goal.

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