What type of chromatography uses a liquid mobile phase?

Liquid chromatography employs a liquid mobile phase to transport samples through the stationary phase, which can be either a solid or a liquid, depending on the specific type being utilized. The use of a liquid mobile phase is essential in facilitating the separation of components within a mixture based on their differing affinities for the stationary and mobile phases. This method allows for effective separation and analysis of compounds that may be sensitive to heat, making it particularly useful in organic chemistry for analyzing a wide range of organic compounds.

Thin layer chromatography also utilizes a liquid mobile phase but typically involves a solid stationary phase coated onto a flat surface, while gas chromatography requires a gaseous mobile phase, thus distinguishing it from liquid chromatography. Column chromatography generally refers to a process that can also use liquid phases but is often classified separately when discussing different chromatography techniques. Therefore, liquid chromatography stands out as the primary choice that distinctly uses a liquid mobile phase in its methodology.